LAB NEWS |
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"Where Imagination can achieve the Impossible"
George M. Low, American Pioneer and Rensselaer Alumni
The Shastrilab is committed to the training of the next generation of scientists in biomaterials, nanoscience, cancer biology and regenerative medicine. We welcome your support of our efforts. If you would like to sponsor one of our scientists or students and/or partner with us to address some of the most pressing challenges of our times then please contact us.
We are a highly inter-disciplinary and international group comprising of materials scientists, polymer chemists, biomedical engineers, and molecular biologists, spanning various nations of Europe, Asia and North America. Our objective is to make a difference through innovation in life sciences. By asking fundamental questions and constructing hypotheses that go against the conventional wisdom, we have evolved and continue to evolve new paradigms in stem cell niche engineering, tumor biology, central nervous system physiology, regenerative medicine, targeted therapeutics and functional imaging. Our motto is “THINK BIG and DO IT NOW”. By emphasizing a "learn it by doing" approach, we empower scientists and individuals at all levels, encouraging them to take ownership of their science, and to go after intractable and complex problems through a hypothesis driven approach to problem solving. Copyright - Shastrilab, All Rights Reserved
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Our Discoveries the Past 5 Years
For complete list click here |
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HOT PAPERS |
Mechanobiology in Angiogenesis - Mechanically-defined hydrogels stabilize blood vessels by recruiting Piezo1+/CD11b+/CD115+ cells. We are honored to receive the cover :) click here for the paper
PR link 
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Autonomous-Mechanobiology in human MSC Chondrogenesis - Aggregating MSCs activate an intrinsic mechanobiology program involving N-Cad/Cav-1 signaling that promotes chondrogenesis even in absence of exogenous growth factors. click here for the paper
PR link phys.org 
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Our Science Makes it to the Cover of University Science Magazine (Uni'wissen) - We are delighted to have Dr. Melika Sarem's doctoral work become the front-piece and main news article in Uni'wissen magazine. We hogged the first 4 images and pages of the issue 😎
check it out here 
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For a more complete list of publications please click here
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Biogenic Apatite - Phosphoprotein Secondary Structure Matters - Low PII- secondary structure is key for biogenic apatite formation. Check out breakthrough paper in Advanced Materials. phys.org
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Stiffness Matters - Engineering the Tumor - Membrane stiffness promotes dynamin mediated endocytosis (DME) and uptake of polymeric nanoparticles. Check out our paper in SMALL
PR link phys.org |
BIOINKS - Lynchpin of 3D-Bioprinting - Check out the next generation of BIOINKS that will drive clinical translation. Check out our paper in Advanced Healthcare Materials.
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